Abstract Objective:
To assess the impact of zinc supplementation on wound healing and tissue regeneration in elderly adults with chronic wounds.

Context:
Zinc is a critical component in the body's wound healing process, contributing to cell proliferation, protein synthesis, and collagen formation. Zinc deficiency is associated with delayed wound healing, particularly in elderly populations who may already have compromised immune responses and slower tissue regeneration due to aging.

Methods Used:
A controlled clinical trial involved 80 elderly participants (ages 65 and above) with chronic wounds (e.g., pressure ulcers). Participants were randomly assigned to receive either 50 mg of zinc sulfate daily or a placebo for 12 weeks. Wound size, healing rate, and zinc levels were measured at baseline, 6 weeks, and 12 weeks.

Researchers' Summary of Findings:
The zinc supplementation group showed a faster reduction in wound size and a higher rate of tissue regeneration compared to the placebo group. By the end of the study, 70% of the zinc group had achieved significant wound closure, while only 40% of the placebo group experienced similar improvements. Additionally, zinc levels in the blood increased, correlating with better healing outcomes.

Health Implications:
Zinc supplementation may accelerate wound healing and improve tissue regeneration, particularly in elderly adults. This suggests that individuals with chronic wounds or those at risk for delayed healing could benefit from increased zinc intake to support faster recovery and improved wound outcomes.