Abstract Summary
Objective: This study examines the effects of zinc supplementation on the wound healing process in individuals with chronic wounds.

Context: Zinc plays a critical role in tissue repair and skin integrity. This study evaluates how zinc supplementation impacts the healing rate of chronic wounds, such as diabetic ulcers and pressure sores.

Methods Used
Approach: A randomized, controlled study with 100 participants aged 50-75, diagnosed with chronic non-healing wounds, was conducted. Participants were randomly assigned to receive either 50 mg of zinc sulfate daily or a placebo for 12 weeks.

Data Collection: Wound healing progress was evaluated at baseline, six weeks, and 12 weeks using wound surface area measurements and clinical assessments of wound closure. Blood samples were taken to measure serum zinc levels throughout the study.

Researchers' Summary of Findings
Impact on Health: The zinc supplementation group showed a 40% faster wound closure rate compared to the placebo group. Serum zinc levels in the supplemented group were significantly higher, correlating with improved healing outcomes.

Health Implications: Zinc supplementation significantly accelerates the wound healing process in individuals with chronic wounds. By supporting tissue repair and reducing healing time, zinc may improve outcomes for patients with long-term skin injuries.

DOI: 10.1016/j.woundheal.2024.512029