Abstract Summary

Objective: This study investigates the effects of fish oil supplementation on cardiovascular health in patients with type 2 diabetes.

Context: Cardiovascular disease is a leading complication of diabetes. The anti-inflammatory effects of omega-3 fatty acids found abundantly in fish oils may benefit cardiovascular health.

Methods Used

Approach: A double-blind randomized placebo-controlled trial with 60 diabetic patients who received either fish oil capsules containing 900mg EPA and 600mg DHA daily or a placebo for 12 weeks.

Data Sources: Blood biomarker data, vascular function tests, and cardiac MRI imaging were used to assess cardiovascular effects.

Researchers' Summary of Findings

Health Implications: Fish oil supplementation significantly improved blood lipid profiles, vascular function as measured by flow-mediated dilation, and left ventricular function compared to placebo. Findings suggest cardiovascular protective effects in diabetics.

DOI: 10.2337/db10-1620