Study Title: Impact of Magnesium on Bone Health in Older Adults: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis, conducted in 2021, investigated the impact of magnesium intake on bone health outcomes in older adults, specifically focusing on bone mineral density (BMD), bone mineral content (BMC), bone turnover markers, and fracture risk.
The review included a systematic search using Embase, Medline Ovid, and Cochrane Central databases, considering studies related to magnesium intake and bone health outcomes in adults aged ≥60 years. It screened 787 records, including six cohort studies, one case-control study, and five cross-sectional studies.
The qualitative evaluation indicated a positive trend between higher magnesium intake and higher hip and femoral neck BMD. The meta-analysis of four studies showed a significant positive association between magnesium intake and hip BMD. However, no associations with BMD at other sites or fractures were found due to limited research. The study suggests the need for more cohort studies and randomized controlled trials to confirm these findings and evaluate the potential of magnesium supplementation in improving bone health in older adults.