Abstract

Objective: This meta-analysis examines whether vitamin C supplementation can prevent or treat respiratory infections.

Context: Vitamin C has antioxidant properties that could potentially boost immune function. But its effects on respiratory illness are unclear.

Methods Used

Approach: A systematic review and meta-analysis methodology was utilized to pool results from randomized controlled trials of vitamin C supplementation on respiratory infections.

Data Collection: 29 trials with over 11,000 participants were included. Vitamin C doses ranged from 0.2 to 6 grams per day administered for 2 weeks to 5 years.

Researchers’ Summary of Findings

Impact on Health: Vitamin C supplementation showed a statistically significant protective effect against pneumonia, but no significant effect on the common cold.

Health Implications: Routine vitamin C supplementation may help prevent pneumonia, especially in those with low dietary intake. Further research is needed to confirm effects.

DOI: 10.1016/j.maturitas.2017.03.313