Abstract 

Objective: This randomized controlled trial investigates the effects of grounding on heart rate variability and inflammatory markers in healthy adults.

Context: Grounding may reduce inflammation and stress by connecting electrically with the earth's surface. However, high-quality evidence on physiological effects is limited.

Methods Used: 64 healthy participants were randomized to either grounded or sham grounding for 8 weeks. Grounding was achieved with a conductive mattress pad. Heart rate variability and inflammatory cytokines were measured at baseline and study end.

Researchers' Summary of Findings: The grounded group showed significant increases in SDNN, total power, and high frequency power compared to sham. IL-6 and TNF-alpha significantly decreased in the grounded group.

Health Implications: Grounding improves heart rate variability metrics related to autonomic function and reduces inflammatory cytokines. This supports potential health benefits of grounding on the cardiovascular and immune systems.

DOI: 10.1016/j.joim.2012.08.001