Abstract

Objective: This study examines the efficacy of vitamin C supplementation in reducing the duration and severity of the common cold.

Context: The common cold is a prevalent illness with significant economic impacts. Vitamin C has been frequently proposed as a supplement to reduce cold symptoms, but past research has shown mixed results.

Methods Used

Approach: A meta-analysis was conducted on randomized controlled trials testing vitamin C supplementation on common cold outcomes like duration and symptom severity.

Data Collection: 29 placebo-controlled studies with over 11,000 participants were included in the meta-analysis. The dosage, frequency and duration of vitamin C supplementation was examined.

Researchers' Summary of Findings

Impact on Health: Regular ingestion of vitamin C was shown to reduce common cold duration by 8% in adults and 14% in children. Supplementation did not affect cold incidence.

Health Implications: Routine vitamin C supplementation can modestly yet statistically significantly reduce the duration of common colds. Further research is needed on optimal dosing regimens.

DOI: 10.1016/S0140-6736(75)92925-5