Can men take hormone supplements?

Abstract Summary

Objective

To determine under what circumstances hormone supplementation is appropriate for men, what benefits it offers, and what risks or limitations exist.

Context

As men age or undergo health changes, some may experience lower endogenous hormone production. This drives interest in hormone supplementation to restore vitality, libido, muscle mass, mood, or energy.

Methods Used

Approach

Review of clinical guidelines from urology and endocrine associations; analysis of clinical studies on therapy outcomes; evaluation of population-level data regarding benefits and side effects.

Data Collection

Data from consensus guidelines indicating criteria for therapy initiation; clinical trial outcomes on muscle mass, libido, bone density, and general health in men receiving hormone therapy; observational data on risks associated with hormone supplementation.

Researchers’ Summary of Findings

• Medical societies recommend hormone supplementation only for men with consistently low hormone (testosterone) levels confirmed by repeated lab tests, alongside clinical symptoms (e.g. fatigue, low libido, reduced muscle mass) — not simply for age-related decline or general wellness.

• When properly indicated and monitored, hormone therapy can improve libido, sexual health, muscle mass, bone density, mood, and other quality-of-life measures in men with deficiency.

• However, there are potential risks and long-term considerations: therapy can suppress the body’s natural hormone production, may affect fertility, alter hematocrit (blood cell counts), and may require ongoing monitoring for prostate health and metabolic parameters.

• For men without clinically low hormone levels, evidence that supplementation significantly improves vitality, energy, or longevity remains weak or inconsistent. Clinical guidelines caution against unnecessary prescribing.

Health Implications

Hormone supplementation can be effective and appropriate — but only under strict medical indication and supervision. Unregulated or unnecessary use, especially for performance or anti-aging reasons, carries potential risks and uncertain long-term benefit. Men should first evaluate lifestyle, nutrition, and health factors before considering supplementation.