Evaluating Vitamin C’s Role in Shortening Common Cold Duration: Evidence from a Placebo-Controlled Study
Abstract Summary
Objective: This study evaluates the effectiveness of Vitamin C supplementation in boosting immune function and reducing the duration of common cold symptoms in adults.
Context: Vitamin C, known for its antioxidant properties, has long been considered a potential agent in enhancing immune responses. This research aims to determine whether daily Vitamin C supplementation can shorten the duration and severity of common cold symptoms in otherwise healthy adults.
Methods Used
Approach: A 12-week, double-blind, placebo-controlled trial was conducted with 150 participants. Each participant received either 1 gram of Vitamin C daily or a placebo during the cold season. The study assessed symptom duration, severity, and overall immune function, monitored via self-reported cold diaries and immune biomarkers, such as C-reactive protein (CRP) levels.
Data Collection: Symptom duration and severity were recorded by participants when experiencing cold symptoms. Blood samples were collected at baseline, mid-study (6 weeks), and after 12 weeks to measure CRP levels and white blood cell counts.
Researchers' Summary of Findings
Impact on Health: The Vitamin C group showed a statistically significant reduction in both the duration and severity of cold symptoms compared to the placebo group. On average, the Vitamin C group experienced cold symptoms for 1.5 days less than the placebo group. CRP levels also decreased in the Vitamin C group, indicating improved immune function.
Health Implications: Daily Vitamin C supplementation appears to boost immune function and reduce the duration of common colds in healthy adults. These findings suggest that Vitamin C can be a valuable supplement during cold seasons for individuals seeking to minimize cold-related discomfort.
DOI: 10.1016/j.immunity2024.508920