Is It Better to Take Probiotics and Prebiotics in the Morning or at Night?
Abstract Summary
Objective
To determine whether morning or nighttime supplementation provides greater efficacy for probiotics and prebiotics.
Context
Probiotics contain live microorganisms sensitive to stomach acid, while prebiotics act as fermentable substrates. Gastric pH, meal timing, and circadian rhythms may affect their performance.
Methods Used
Approach
Randomized timing trials compared bacterial survival rates and symptom responses when supplements were taken fasting, with meals, or before sleep.
Data Collection
Stool samples, microbial diversity analysis, gastrointestinal symptom logs, and capsule survivability testing were collected across multiple dosing schedules.
Researchers' Summary of Findings
Impact on Health
Morning or daytime intake improved adherence and reduced sleep-disrupting digestive symptoms.
Health Implications
Consistency matters more than exact timing. Individuals prone to bloating benefit from avoiding nighttime prebiotic intake.
Sustainability
Optimized timing reduces supplement overuse and improves efficiency, supporting responsible consumption.
DOI
