Reishi Mushroom Interactions: What You Should Not Mix It With

Abstract Summary

Objective

To identify known contraindications and clinically relevant interactions associated with reishi supplementation.

Context

Reishi exhibits immunomodulatory, antihypertensive, and anticoagulant properties. These effects may amplify or interfere with pharmaceutical treatments targeting similar pathways.

Methods Used

Approach

Case reports, pharmacological analyses, and clinical observations were reviewed to assess adverse interactions between reishi and commonly prescribed medications.

Data Collection

Data included coagulation markers, blood pressure measurements, immune response indicators, medication histories, and reported adverse events.

Researchers' Summary of Findings

Impact on Health

Potential interactions were observed with anticoagulants, antihypertensive drugs, and immunosuppressive therapies, particularly with long-term or high-dose use.

Health Implications

Medical supervision is recommended when reishi is combined with prescription medications affecting blood clotting, immune response, or cardiovascular function.

Sustainability

Responsible and informed use of reishi minimizes adverse effects while preserving its long-term therapeutic potential.

DOI

10.1016/j.jep.2019.111829